1.Ma Xinyu, Zhu Yuwei, Dong De, Chen Yan &Huang Zhiwei^# 

Cryo-EM structures of two human B cell receptor isotypes

Science

2.Guo Minghui, Zhu Yuwei, Lin Zhiying, &Huang Zhiwei^# 

Cryo-EM structure of the type III-E CRISPR-Cas effector gRAMP in complex with TPR-CHAT

Cell Research

3. Zhao Yanan &Yang Fan^#    

A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1

Nature Communications

4. Zhu Xinyan &He Yuanzheng^#

Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling

Nature Communications

5. Li Xinzhi, Ding Kaixin & Chen Zheng^# 

Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis NASH

Nature Communications

6. Wang Na & He Yuanzheng^#   

Structural basis of leukotriene B4 receptor 1 activation

Nature Communications

7. Chen Yan, Zhu Yuwei, Li Xiang, Gao Wenbo & Huang Zhiwei^#  

Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility

Molecular Cell

8. Qian Yu & He Yuanzheng^#           

Structural insights into adhesion GPCR ADGRL3 activation and Gq、Gs、Gi、G12 coupling

Molecular Cell

9.Xu Zhenmei, Tatsuya Ikuta & He Yuanzheng^#      

Structural basis of sphingosine-1-phosphate receptor 1 activation and biased agonism

Nature Chemical Biology

10.Wang Xingwen, Zheng Shanliang & Hu Ying^#      

LncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma

Molecular Therapy

11.Zheng Shanliang, Wang Xingwen & Hu Ying^#      

iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers

Cell Death and Differentiation

12.Setu M Vora & Shi Ming^#

Targeting Stem-loop 1 of the SARS-CoV-2 5’UTR to suppress viral translation and Nsp1 evasion

Proceedings of the National Academy of Sciences of the United States of America

13.Zheng Shanliang & Hu Ying^# 

iASPP suppresses Gp78-mediated TMCO1 degradation to maintain Ca²⁺ homeostasis and control tumor growth and drug resistance

Proceedings of the National Academy of Sciences of the United States of America